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Product Details for Biolytic 3900 OLIGO SYNTHESIZER - New!

Category: DNA/RNA Synthesizers
Price: Call for price.
Photo:   Biolytic 3900 OLIGO SYNTHESIZER - New!
Product Information:


High Performance Medium Throughput

Blue Lion Biotech is able to bring you a 3900 Oligo Synthesizer from Biolytic that dramatically improves performance vs the the ABI 3900, adds hardware features and comes with a completely new software package, written from the ground up, to run on the latest version of Windows. Whether you are looking for a NEW Biolytic 3900, ABI 3900 service, ABI 3900 parts or an ABI 3900 upgrade, please consider Blue Lion Biotech for all of your 3900 needs.

Blue Lion Biotech is an authorized Biolytic Distributor.

Starting life as an ABI 3900, the Biolytic 3900 is an upgrade of the original ABI 3900 that comes packed with new hardware and re-imagined software features as well as a new computer and monitor running the latest Windows operating system. The new software is built for Windows 8 and features flexible protocol construction similar to the world renowned Dr. Oligo Synthesizer. The software supports truly independent protocol operation on each bank of 12 oligos while providing the user with real-time feedback during each synthesis run.

With over two decades of applied experience in the field of oligonucleotide synthesis automation, Biolytic together with Blue Lion Biotech are able to bring you a 3900 that dramatically improves performance, adds hardware features and comes with a completely new software package, written from the ground up.

The patent pending Biolytic 3900 greatly reduces cycle time due to the use of 4 drain stations rather than the original 2. The chamber volume is much lower, requiring less time to pressurize and vent.The ABI 3900 Oligo Synthesizer has become very popular for synthesis of standard and special oligos. ABI has not supported this product for several years even though there are many instruments in service to this day. The ABI 3900 instrument and software have remained fundamentally unchanged since its release.

The Biolytic 3900 adds a mechanism to move reagents slowly through the columns creating maximum reaction site efficiency. This allows the use of less reagent while achieving a high reaction efficiency. Most oligos are synthesized using CPG or polystyrene support columns.

The reaction sites within the solid supports are in tight spaces (such as CPG pores), requiring time for reagent to diffuse to the reaction sites. The ability to precisely control reagent flow through the columns allows more efficient diffusion to reaction sites, resulting in higher reaction efficiency even with the use of smaller volumes of reagents.

The patent pending Biolytic 3900 also allows finely tuned control of reaction chamber pressure above and below synthesis columns, preventing liquid from flowing backwards up through columns and eliminating the risk that back flowing reagents may contaminate adjacent syntheses.

The Chamber Flood Damage Control System redirects chamber flood reagents to waste. In the unlikely event of a reagent overflow, excess liquid in the reaction chamber is directed to a waste trough away from the motion control assembly. This protects the motion control assembly from chemical damage, preventing the need for potentially costly and time-consuming repairs.

Truly independent protocol operation on each bank of 12 oligos. The pressure below each bank of 12 synthesis columns is controlled independently, allowing the simultaneous use of up to 4 different protocols in a single synthesis.

Allows use of up to 10 specials. The amidite delivery is highly customizable, allowing any amidite nozzle to dispense to any column position, permitting the use of up to 10 special amidites in addition to the 4 standard amidites used.

Ability to simultaneously use 2 different Oxidizer reagents.The software package allows the use of more than one oxidizer, and permits the configuration of each amidite to automatically select the correct oxidizer to be used in each step of the synthesis. Among other applications, this allows oxidation and sulfurization to be performed in the same synthesis.

Flexible protocol construction. There is no need to use Excel to edit and create protocols. Biolytic's protocol editor uses familiar Drag-and-Drop to edit and create protocols. Select from a range of standard protocols supplied with the software, or finely tune your protocols to meet you individual synthesis needs.


Blue Lion Biotech fully understands the economic difficulties and challenges involved in today’s research environment. We support the biotech community and offer special discounts for qualifying customers. Call for details.


Call (425)-396-4441 or email Blue Lion Biotech at today for price.

We look forward to working with you.


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