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Product Details for DR. OLIGO 192C DNA SYNTHESIZER - NEW

Category: DNA/RNA Synthesizers
Price: Call for price.
Product Information:


Together Biolytic Lab Performance, Inc. and Blue Lion Biotech are proud to introduce the Dr. Oligo 192c – Biolytic’s latest high throughput oligo synthesizer. Now restructured with all the same principles that helped Biolytic to become the industry's gold standard, the 192c is a faster, more compact model that can adapt to fit the various needs of our customers. This instrument came to life through innovative ideas of quality improvement, upgraded features and cost-efficiency - all of which have allowed us to provide Biolytic’s proven reliability at a much more affordable price. The Dr. Oligo 192c is truly an advancement in high throughput oligo synthesis.

Customers all over the world use nucleic acids produced by our Dr. Oligo synthesizers for their own unique purposes. From applications like oligonucleotide and gene synthesis, genetic test kits, PCR/RT-PCR, siRNA/RNAi, miRNA, CRISPR Cas9, and DNA/RNA sequencing - to broader areas like evolutionary history, forensics, immuno- therapy, diagnostic and therapeutic research – to high-throughput screening, natural product biosynthesis, reverse transcription PCP, hybridization, and SNPS – the variety is tremendous. Recently some have even endeavored into using nucleic acids as computer information storage devices, storing animated videos in DNA. The Dr. Oligo line has evolved alongside these cutting-edge discoveries, and with the 192c it will continue to play a significant role in modern science.


Reduced Footprint

The Dr. Oligo 192c has been reduced in volume by more than 40% from the original 192,* taking up just a fraction of the space in your lab.

Secure Bottle Containment System

A new bottle containment system protects the instrument and its users against spills and breakage. Your bottles are safely isolated behind a transparent door, and in the event of breakage, our innovative sealed catch tray drains directly to waste.


Our Dr. Oligo 192c base model is compatible with up to 10 reagents - 4 standard and up to 6 additional reagents of any combination of the following: specials, second oxidation, double deblock or double wash. The open-frame structure of this instrument provides many opportunities for customization, supporting increased reagent counts and throughput.


Maintenance is made simpler. Purge, drain and pneumatic plumbing is physically separate from the bottle system, enabling easy and individual access. This industry-leading design creates unparalleled efficiency and serviceability.

Certified Training

As with all of our instruments, Biolytic Certified Training (CIT) is available for the Dr. Oligo 192c. Upon successful completion of the certificate program, recipients will be able to understand the function of the instrument, how to operate it, and how to perform basic troubleshooting. This training, coupled with the 192c’s simple maintenance, will decrease total operation costs for the 192c. Please contact our sales department for more information and restrictions on this optional program.

*Excludes slider plate

Biolytic Boards

The debut of the Dr. Oligo 192c is also the introduction of our new Driverless Biolytic Control Boards. The control boards consist of 32 outputs and 8 inputs, designed by Biolytic specifically for our Dr. Oligo synthesizer line. They ensure proper dispensing of as little as 2ul* and are complete with an antistatic, shockproof design, on-board timing, valve short protection, valve flood protection, and real-time monitoring of valve electrical integrity.

Improved Software

The 192c software has faster loading times, updated user interface, advanced security, and a new Hardware Monitoring System.

Security and Encryption

The software offers encrypted communication, which increases system uptime and improves the overall quality of each synthesis.

Hardware Monitoring System

This new feature keeps operators updated on the status of instrument hardware, including the Biolytic Boards and motor. The system works in conjunction with our control boards to prompt users to take action in the event of hardware failure.

Ease of Use

Side-by-side Slider Plate Windows

The Dr. Oligo 192c nozzle plate windows are now located side-by-side, a reconfiguration that allows users to oversee both reaction plates at the same time. 

LED Bottle Backlighting

We have also added chemically safe LED backlighting to the bottle compartment, which makes monitoring reagent levels more convenient and ensures that the instrument is always prepared for synthesis.

Increased Efficiency

Our original 192 model came with a manual washing system and an additional automated wash option. The 192c redefines that standard by including nozzle washing with every instrument. The reagent delivery system is now made with smaller valves and fills with less volume, thus cutting down unnecessary costs by reducing waste and allowing for faster, more consistent response times.


Simply the best high throughput Oligo synthesizer in the world!

The 192c has 8 dispensing nozzles per reagent.

The maximum # of reagent delivery positions: 16.

Basic Configuration Comes with 4 standard amities: Cap A, Cap B, ACT, 1 Wash, 1 Deblk, 1 Ox = 10 total

Additional available positions: 6


2nd Ox, Special Amities 2nd Wash, 2nd Deblock, Cart

3 day Domestic Installation & Training

**The system comes with 1 standard amidite bottle per standard amidite. The benefit of adding the second bottle w/caps is in a situation where the amidite runs low and you need more you will not have to pour it into the bottle to continue, the 2nd bottle automatically feeds it. Truly a great feature at a minimal cost.


Blue Lion Biotech fully understands the economic difficulties and challenges involved in today’s research environment. We support the biotech community and offer special discounts for qualifying customers. Call for details.


Call (425)-396-4441 or email Blue Lion Biotech at today for price.

We look forward to working with you.


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